When following the guidelines of HBN4 Supplement 1: Isolation facilites in acute settings the VARI-centric Bespoke Air Pressure Stabilisers are utilised to maintain the positive pressurisation lobby ensuring that air from the corridor does not enter the isolation room, and that air from the room does not escape into the corridor. This basic but effective design enables the suite to be used for both source and protective isolation without the need for switchable ventilation or special training for staff. Importantly it also provides safe isolation for those patients whose exact condition is unknown.